The only way to link multiple plots to the same data set would be through the use of DDE under Windows. You could maintain the original data in Excel and link to the data from within KaleidaGraph. Any plots created from the linked data would be updated when the data changes.
KaleidaGraph is a thoughtfully designed graphing and data analysis application for research scientists, as well as for those in business and engineering fields. It produces publication-quality graphs, and easily converts the most complex data into a functional display.