Unless you have v4.x, there is no way to save the plots and layout in a single file. The layout file in earlier versions only remembers the cells and any text or other graphics that were included in the layout. In v4.x, you can save plots and layouts together in a Group Layout file.
KaleidaGraph is a thoughtfully designed graphing and data analysis application for research scientists, as well as for those in business and engineering fields. It produces publication-quality graphs, and easily converts the most complex data into a functional display.